microbeMASST, a taxonomically informed mass spectrometry (MS) search tool, tackles limited microbial metabolite annotation in untargeted metabolomics experiments. Leveraging a curated database of >60,000 microbial monocultures, users can search known and unknown MS/MS spectra and link them to their respective microbial producers via MS/MS fragmentation patterns. Identification of microbe-derived metabolites and relative producers without a priori knowledge will vastly enhance the understanding of microorganisms’ role in ecology and human health.
Zuffa S., Schmid R., Bauermeister A., Gomes P. W. P., Caraballo-Rodriguez A. M., El Abiead Y., Aron A. T., Gentry E. C., Zemlin J., Gindro K., Massana Codina J., Dorrestein P.
microbeMASST: A taxonomically informed mass spectrometry search tool for microbial metabolomics data.
Nature Microbiology, 9, 2024, 336-345.
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ISSN Online: 2058-5276
Digital Object Identifier (DOI): https://doi.org/10.1038/s41564-023-01575-9
ID pubblicazione (Codice web): 55791 Inviare via e-mail
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